Lee Josephson Selected Research

viridin

8/2009	Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function.
12/2008	Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation.

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Lee Josephson Research Topics

Disease

29	Neoplasms (Cancer) 10/2021 - 01/2002
5	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2021 - 01/2018
4	Inflammation (Inflammations) 06/2015 - 12/2008
4	Breast Neoplasms (Breast Cancer) 01/2014 - 12/2007
3	Fibrosis (Cirrhosis) 01/2022 - 01/2020
3	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 01/2019
3	Ischemia 01/2017 - 04/2012
3	Necrosis 02/2015 - 11/2009
3	Gliosarcoma 04/2006 - 04/2003
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 01/2020
2	Neuroinflammatory Diseases 12/2021 - 01/2018
2	Anemia 01/2020 - 01/2018
2	Schizophrenia (Dementia Praecox) 01/2019 - 09/2018
2	Parkinson Disease (Parkinson's Disease) 01/2019 - 01/2018
2	Neoplasm Metastasis (Metastasis) 05/2012 - 02/2002
2	Infarction (Infarctions) 04/2012 - 11/2011
2	Prostatic Neoplasms (Prostate Cancer) 08/2011 - 10/2005
2	Lewis Lung Carcinoma 10/2005 - 04/2003
2	Carcinoma (Carcinomatosis) 01/2005 - 04/2003
1	Reperfusion Injury 01/2022
1	Hepatocellular Carcinoma (Hepatoma) 01/2022
1	Liver Diseases (Liver Disease) 01/2022
1	Starvation 01/2022
1	Coronary Artery Disease (Coronary Atherosclerosis) 10/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 10/2021
1	Substance-Related Disorders (Drug Abuse) 10/2019
1	Central Nervous System Diseases (CNS Diseases) 01/2019
1	Non-alcoholic Fatty Liver Disease 01/2019
1	Epilepsy (Aura) 09/2018

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 12/2021 - 04/2003
7	Fluorescent Dyes (Fluorescent Probes)IBA 01/2014 - 08/2004
5	IntegrinsIBA 01/2020 - 03/2006
5	AnnexinsIBA 02/2015 - 04/2003
4	EnzymesIBA 01/2022 - 12/2008
4	Pharmaceutical PreparationsIBA 01/2020 - 12/2007
4	Annexin A5IBA 02/2015 - 04/2003
4	Peptides (Polypeptides)IBA 01/2013 - 10/2005
3	LigandsIBA 01/2022 - 12/2021
3	IronIBA 01/2020 - 06/2015
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 05/2003
3	Ferrosoferric Oxide (Magnetite)FDA Link 01/2020 - 02/2015
3	ferric oxide (iron oxide)IBA 12/2015 - 03/2006
3	Green Fluorescent ProteinsIBA 04/2006 - 02/2002
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 08/2004 - 04/2003
2	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2022 - 01/2020
2	Monoacylglycerol LipasesIBA 01/2022 - 10/2019
2	Radioisotopes (Radionuclides)IBA 01/2020 - 01/2013
2	Chemokine ReceptorsIBA 01/2018 - 12/2011
2	cyclic arginine-glycine-aspartic acid peptideIBA 10/2017 - 03/2006
2	Antineoplastic Agents (Antineoplastics)IBA 10/2017 - 05/2003
2	Photosensitizing Agents (Photosensitizers)IBA 10/2017 - 01/2013
2	DNA (Deoxyribonucleic Acid)IBA 03/2013 - 11/2011
2	Cy5.5-annexin V conjugateIBA 04/2012 - 11/2009
2	GadoliniumIBA 11/2011 - 11/2009
2	Gadolinium DTPA (Magnevist)FDA Link 11/2011 - 11/2009
2	viridinIBA 08/2009 - 12/2008
2	ProdrugsIBA 08/2009 - 12/2008
2	Peptide Hydrolases (Proteases)FDA Link 08/2009 - 05/2009
2	Telomerase (Telomerase Reverse Transcriptase)IBA 10/2008 - 01/2004
2	Trastuzumab (Herceptin)FDA Link 09/2008 - 12/2007
2	Biological ProductsIBA 12/2007 - 05/2005
2	CY5.5 cyanine dyeIBA 04/2006 - 04/2003
2	E-SelectinIBA 10/2005 - 01/2002
2	Contrast MediaIBA 12/2003 - 02/2002
1	1-dodecylpyridoxal (PLD)IBA 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2022
1	CannabinoidsIBA 01/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 10/2021
1	diethylstilbestrol monophosphate (PDES)IBA 10/2021
1	Cathepsin DIBA 01/2020
1	Amyloid (Amyloid Fibrils)IBA 01/2020
1	Cholesterol 24-Hydroxylase (CYP46A1)IBA 01/2020
1	Leucine (L-Leucine)FDA Link 01/2019
1	xanomelineIBA 01/2019
1	Molecular Probes (Molecular Probe)IBA 01/2019
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2019
1	AMPA Receptors (AMPA Receptor)IBA 09/2018
1	AcidsIBA 09/2018
1	GTP-Binding Proteins (G-Protein)IBA 01/2018
1	Phospholipases A2 (Phospholipase A2)IBA 01/2018
1	Immunoglobulins (Immunoglobulin)IBA 01/2018
1	SynucleinsIBA 01/2018
1	Natriuretic PeptidesIBA 01/2018
1	Glycogen Synthase Kinase 3IBA 01/2018
1	Monoamine Oxidase (MAO)IBA 01/2018
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2018
1	Arachidonic Acid (Vitamin F)IBA 01/2018
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2018
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2018
1	Receptor for Advanced Glycation End ProductsIBA 01/2018
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2018
1	Purinergic Receptors (Receptors, Purine)IBA 01/2018
1	Triggering Receptor Expressed on Myeloid Cells-1IBA 01/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018

Therapy/Procedure

12	Therapeutics 01/2020 - 12/2003
4	Drug Therapy (Chemotherapy) 01/2022 - 05/2003
2	Ligation 01/2022 - 01/2020
2	Precision Medicine 11/2020 - 01/2017
2	Lasers (Laser) 02/2015 - 09/2008